Structure of a bacterial peptide pheromone/receptor complex and its mechanism of gene regulation

Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis.

MFKIGSVLKQIRQELNYHQIDLYSGIMSKSVYIKVEADSRPISVEELSKFSERLGVNFFEILNRAGMNTKSVNETGKEKL
LISKIFTNPDLFDKNFQRIEPKRLTSLQYFSIYLGYISIAHHYNIEVPTFNKTITSDLKHLYDKRTTFFGIDYEIVSNLL
NVLPYEEVSSIIKPMYPIVDSFGKDYDLTIQTVLKNALTISIMNRNLKEAQYYINQFEHLKTIKNISINGYYDLEINYLK
QIYQFLTDKNIDSYLNAVNIINIFKIIGKEDIHRSLVEELTKISAKEKFTPPKEVTMYYENYVAIENNPIPEIKEQS

PEG4000, citrate-phosphate, pH 7.0, EVAPORATION, temperature 298K

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

Repressor, pheromone, DNA binding, regulatory, TRANSCRIPTION