Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds.
The submitted conformer models are those with the fewest number of constraint violations.
3D HNCACB, 3DHNCO, 3D CBCACONH, 3D HBHA(CBCACO)NH, 3D (H)C(CO)NH-TOCSY, H(CCO)NH-TOCSY, 2DTOCSY, 2D-CBHD, 2DCBHE, 2D TOCSY
A219 mutant protein, 2 mM ammonium bicarbonate buffer, pH 7.0, 10% D2O
2 mM ammonium bicarbonate buffer, 10% D2O.
Frank Delaglio, Stephan Grzeiek, Guang Zhu, Geerten W. Vuister, John Pfeifer and Ad Bax
A.T.Brunger, P.D.Adams, G.M.Clore, W.L.Delano, P.Gros, R.W.Grosse-Kunstleve, J.-S.Jiang, J.Kuszewski, M.Nilges, N.S.Pannu, R.J.Read, L.M.Rice, T.Simonson, G.L.Warren
IgG-binding, protein A, phage display, Immune System-Protein Binding COMPLEX