Solution structure of the human Mms2-Ubiquitin complex
Structural Basis for Non-Covalent Interaction Between Ubiquitin and the Ubiquitin Conjugating Enzyme Variant Human MMS2.
Ubiquitin-conjugating enzyme E2 variant 2
MMS2, Enterocyte differentiation associated factor EDAF-1, Enterocyte differentiation promoting factor, EDPF-1, Vitamin D3 inducible protein, DDVit 1
VKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKI NMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN
Sequence Yeast Ubiquitin was used to obtain restraint information, while human Ubiquitin was used to model the interaction. The sequence differences between yeast and human Ubiquitin are absent from the protein-protein binding interface.
Delaglio, F., Grzesiek, S., Vuister, G.W., Zhu, G., Pfeifer, J., Bax, A.
Dominguez, C., Boelens, R., Bonvin, A.M.J.J.
UEV domain, ubiquitin binding motif, LIGASE-SIGNALING PROTEIN COMPLEX