Solution structure of human sulfiredoxin (srx)
GAPEGPGPSGGAQGGSIHSGRIAAVHNVPLSVLIRPLPSVLDPAKVQSLVDTIREDPDSVPPIDVLWIKGAQGGDYFYSF GGCHRYAAYQQLQRETIPAKLVQSTLSDLRVYLGASTPDLQ
Crystal structure of human sulfiredoxin (srx)
structures with the least restraint violations
the first 20 residues (17-36) are flexible random coil; no restraints were used for these residues
distance geometry followed by simulated annealing
0.7mM sulfiredoxin U-15N; 50mM phosphate, 100mM NaCl, 2mM DTT
0.7mM sulfiredoxin U-15N,13C; 50mM phosphate, 100mM NaCl, 2mM DTT
Schwieters, Kuszewski, Tjandra, Clore, Brunger