Crystal structure of apple ACC synthase in complex with L-vinylglycine

2-[O-PHOSPHONOPYRIDOXYL]-AMINO- BUTYRIC ACID
VITAMIN B6 COMPLEXED WITH 2-AMINO-BUTYRIC ACID

Structure of ACC synthase inactivated by the mechanism-based inhibitor L-vinylglycine.

1-aminocyclopropane-1-carboxylate synthase

ACC synthase, S-adenosyl-L-methionine methylthioadenosine-lyase

MRMLSRNATFNSHGQDSSYFLGWQEYEKNPYHEVHNTNGIIQMGLAENQLCFDLLESWLAKNPEAAAFKKNGESIFAELA
LFQDYHGLPAFKKAMVDFMAEIRGNKVTFDPNHLVLTAGATSANETFIFCLADPGEAVLIPTPYYPGFDRDLKWRTGVEI
VPIHCTSSNGFQITETALEEAYQEAEKRNLRVKGVLVTNPSNPLGTTMTRNELYLLLSFVEDKGIHLISDEIYSGTAFSS
PSFISVMEVLKDRNCDENSEVWQRVHVVYSLSKDLGLPGFRVGAIYSNDDMVVAAATKMSSFGLVSSQTQHLLSAMLSDK
KLTKNYIAENHKRLKQRQKKLVSGLQKSGISCLNGNAGLFCWVDMRHLLRSNTFEAEMELWKKIVYEVHLNISPGSSCHC
TEPGWFRVCFANLPERTLDLAMQRLKAFVGEYYNVPEVNGGSQSSHLSHSRRQSLTKWVSRLSFDDRGPIPGR

PEG 4000, Tris, NiCl2, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K

the native structure of apple ACC synthase

the structure of apple ACC synthase in complex with the inhibitor L-Aminoethoxyvinylglycine

the structure of apple ACC synthase in complex with an amino-oxy analogue of the substrate