Solution structure of the Cu(I) form of the sixth soluble domain A69P mutant of Menkes protein
An atomic-level investigation of the disease-causing A629P mutant of the Menkes protein, ATP7A
Copper pump 1, Menkes disease-associated protein
the apo form of the same protein, A69P mutant
the structures were based on a total of 1901 meaningful distance constraints, 81 dihedral angle restraints
torsion angle dynamics coupled with simulated annealing followed by restrained energy minimization
0.8mM 15N labeled sample; 5mM DTT; 100mM phosphate buffer
0.8mM 15N 13C labeled sample; 5mM DTT; 100mM phosphate buffer
1.0mM unlabeled sample; 5mM DTT; 100mM phosphate buffer
metallochaperone, protein-protein interaction, copper(I), metal homeostasis, hydrolase