Crystal Structure of the SAM-dependent methyltransferase from Pyrococcus horikoshii OT3

RIKEN Structural Genomics/Proteomics Initiative (RSGI)

MYELYTLLAEYYDTIYRRRIERVKAEIDFVEEIFKEDAKREVRRVLDLACGTGIPTLELAERGYEVVGLDLHEEMLRVAR
RKAKERNLKIEFLQGDVLEIAFKNEFDAVTMFFSTIMYFDEEDLRKLFSKVAEALKPGGVFITDFPCWFYGGRDGPVVWN
EQKGEEKLVIMDWREVEPAVQKLRFKRLVQILRPNGEVKAFLVDDELNIYTPREVRLLAEKYFEKVKIYGNLKRELSPND
MRYWIVGIAKSF

PEG 3350, Magnesium sulfate, pH 5.9, microbatch, temperature 295K

RIKEN Structural Genomics/Proteomics Initiative

The biological assembly is a hexamer generated from the trimer in the asymmetric unit by the operations: x, 1-y, 1-z.

SAM-dependent methyltransferase, structural genomics, RIKEN Structural Genomics/Proteomics Initiative, RSGI, Transferase