Solution structure of the human FES SH2 domain
RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Solution structure of the Src homology 2 domain from the human feline sarcoma oncogene Fes
NMR assignment of the SH2 domain from the human feline sarcoma oncogene FES
Proto-oncogene tyrosine-protein kinase FES/FPS
GSSGSSGEVQKPLHEQLWYHGAIPRAEVAELLVHSGDFLVRESQGKQEYVLSVLWDGLPRHFIIQSLDNLYRLEGEGFPS IPLLIDHLLSTQQPLTKKSGVVLHRAVPSGPSSG
RIKEN Structural Genomics/Proteomics Initiative
structures with the least restraint violations
automated NOESY assignment, torsion angle dynamics, energy minimization
1.2mM uniformly 13C and 15N labeled protein; 20mM Tris-HCl buffer; 100mM NaCl; 1mM dithiothreitol; 0.02% NaN3
SH2 domain, FES, feline sarcoma oncogene, structural genomics, RIKEN Structural Genomics/Proteomics Initiative, RSGI, Transferase
EVQKPLHEQLWYHGAIPRAEVAELLVHSGDFLVRESQGKQEYVLSVLWDGLPRHFIIQSLDNLYRLEGEGFPSIPLLIDH LLSTQQPLTKKSGVVLHRAVP