The crystal structure of a binary U5 snRNP complex

Structural basis for the bifunctionality of the U5 snRNP 52K protein (CD2BP2).

Spliceosomal U5 snRNP-specific 15 kDa protein

CD2 antigen cytoplasmic tail-binding protein 2

U5-15kD; DIM1 protein homolog; Thioredoxin-like U5 snRNP protein U5-15kD; thioredoxin-like 4

CD2BP2; CD2 cytoplasmic domain binding protein; CD2 tail binding protein

MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYLVDITEVPDFNKMYELYDPCT
VMFFFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIETVYRGARKGRGLVVSPKDYSTKYRY

AEEELETPTPTQRGEAESRGDGLVDVMWEYKWENTGDAELYGPFTSAQMQTWVSEGYFPDGVYCRKLDPPGGQFYNSKRI
DFDLYT

PEG 2000mme, MES, calcium acetate, 1,4-butanediol, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K

The crystal structure of one of the components

The NMR structure of the other component

GYF-domain; thioredoxin-like; spliceosomal proteins, TRANSLATION-IMMUNE SYSTEM COMPLEX