STRUCTURAL DETERMINANTS OF PEPTIDE-BINDING ORIENTATION AND OF SEQUENCE SPECIFICITY IN SH3 DOMAINS
The Sh2 and SH3 Domains of Mammalian Grb2 Couple the Egf Receptor to the Ras Activator Msos1
C. Elegans Cell-Signalling Gene Sem-5 Encodes a Protein with Sh2 and SH3 Domains
10-RESIDUE PROLINE-RICH PEPTIDE FROM MSOS (ACE-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG)
MOLECULE_NAME: MSOS, 10-RESIDUE PEPTIDE (ACE-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG). PEPTIDE IS FROM BIOLOGICAL SEQUENCE, BUT IS CHEMICALLY SYNTHESIZED.
SSBOND CRYSTALS GROWN IN THE PRESENCE OF DTT; DISULFIDE BOND THOUGHT TO FORM AFTER INITIAL EXPOSURE TO X-RAYS; CAUSED STABLE SHIFT IN UNIT CELL DIMENSIONS.
SEX MUSCLE ABNORMAL PROTEIN 5, 10-RESIDUE PROLINE-RICH PEPTIDE FROM MSOS (ACE-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG)
SRC-HOMOLOGY 3 (SH3) DOMAIN, PEPTIDE-BINDING PROTEIN, GUANINE NUCLEOTIDE EXCHANGE FACTOR, SIGNAL TRANSDUCTION PROTEIN
MEAVAEHDFQAGSPDELSFKRGNTLKVLNKDEDPHWYKAELDGNEGFIPSNYIRMTECNWYLGKITRNDAEVLLKKPTVR DGHFLVRQCESSPGEFSISVRFQDSVQHFKVLRDQNGKYYLWAVKFNSLNELVAYHRTASVSRTHTILLSDMNVETKFVQ ALFDFNPQESGELAFKRGDVITLINKDDPNWWEGQLNNRRGIFPSNYVCPYNSNKSNSNVAPGFNFGN