Three dimensional solution structure of the R29A MUTANT of sodium channels inhibitor HAINANTOXIN-IV by 2D 1H-NMR
Structure--activity relationships of hainantoxin-IV and structure determination of active and inactive sodium channel blockers
Synthesis and Oxidative Refolding of Hainantoxin-Iv
Isolation and characterization of hainantoxin-IV, a novel antagonist of tetrodotoxin-sensitive sodium channels from the Chinese bird spider Selenocosmia hainana
Three-dimensional solution structure of HAINANTOXIN-IV
synthesized using standard fmoc chemistry.
this structure was determined using standard 2D homonuclear techniques.
the structures are based on 366 NOE- derived distance constraints, 15 dihedral angle restraints, 9 fake distance restraints from disulfide bonds and 12 hydrogen- bond constrains.
20mM deuterium acetic acid BU, 90% H2O, 10% D2O
Neurotoxin, Inhibitor cystine knot motif, TOXIN