Crystal structure of Arthrobacter aurescens chondroitin AC lyase

2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid

N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE

High-resolution crystal structure of Arthrobacter aurescens chondroitin AC lyase: an enzyme-substrate complex defines the catalytic mechanism

2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose

EAEPGAAEFAALRNRWVDQITGRNVIQAGDPDFAKAITALNNKAADSLAKLDAAAGRTSVFTDLSLAKDAEMVTTYTRLS
QLATAWATPTAAVFGDAAVLAAIKAGLADANTLCYNDRKEEVGNWWSWEIGVPRALADAMVLLHAELSAAERTAYCAAID
HFVPDPWLQFPPKRGKITSVGANRVDLCQGIIIRSLAGEDPTKLNHAVAGLSQVWQYVTSGDGIFRDGSFIQHSTTPYTG
SYGVVLLTGLSKLFSLLGGTAFEVSDPTRSIFFDAVEGSFAPVMINGAMADAVRGRSISREANTGYDLGASAIEAILLLA
RAMDPATAARWRGLCAGWIARDTYRPILNSASVPRTALVKQLEATGVAPVAEATGHKLFPAMDRTMHRGPGWALSLALSS
NRIAWYECGNGENNRGYHTGSGMTYFYTSDLGQYDDAFWATANYNRLPGITVDTTPLPDKVEGQWGAAVPADEWSGATAL
GEVAAVGQHLVGPGRTGLTARKSWFVSGDVTVCLGADISTASGAKVETIVDHRNLHQGSNTLTTAAGTIAGTAGTVEVLG
DGRWVHLEGFGGYAMLDDSPLHVLRETRSGSWSGVNINGSATVQQRNFATLYVNHGVGPVAGSYAYMVAPGASVDLTRKL
LEGNKYSVIRNDATAQSVEFKTAKTTAATFWKPGMAGDLGASGPACVVFSRHGNELSLAVSEPTQKAAGLTLTLPEGTWS
SVLEGAGTLGTDADGRSTLTLDTTGLSGKTKLIKLKR

PEG 8000, ammonium acetate, glycerol, phosphate buffer, pH 6.4, VAPOR DIFFUSION, HANGING DROP, temperature 293K

HETEROGEN
SUGAR CHAIN D (GAD 809)-(NAG 810) IS HYALURONIC ACID
DISACCHARIDE.

chondroitin lyase, chondroitinase, hyaluronan, lyase