Structure-activity relationships for the beta-hairpin cationic antimicrobial peptide polyphemusin I.
SEQUENCE At the time of processing, no reference sequence was present in the sequence database for this species, Tachypleus polyphemus (american horeshoe crab).
THE PEPTIDE WAS CHEMICALLY SYNTHESIZED USING FMOC SOLID STATE SYNTHESIS. THE SEQUENCE OF THE PEPTIDE IS NATURALLY FOUND IN TACHYPLEUS POLYPHEMUS (AMERICAN HORESHOE CRAB).
This structure was determined using standard 2D homonuclear techniques.
DISTANCE GEOMETRY WITH SIMULATED ANNEALING
POLYPHEMUSIN, BETA HAIRPIN, DISULFIDE BRIDGE, ANTI-MICROBIAL PEPTIDE, ANTIMICROBIAL PEPTIDE