DNA DECAMER DUPLEX CONTAINING T5-T6 PHOTOADDUCT
[3-HYDROXY-5-(5-METHYL-2,4-DIOXOTETRAHYDRO-1(2H)-PYRIMIDINYL)TETRAHYDRO-2-FURANYL]METHYL DIHYDROGEN PHOSPHATE
Solution Structure of a DNA Decamer Duplex Containing the 3' T.T Base Pair of the Cis-Syn Cyclobutane Pyrimidine Dimer: Implication for the Mutagenic Property of the Cis-Syn Dimer.
CYCLOBUTANE RING FORMED BETWEEN C5-C6(T5) AND C5-C6(T6) DOUBLE BONDS
DNA (5'-D(*CP*GP*CP*AP*TP*+TP*AP*CP*GP*C)- 3')
DNA (5'-D(*GP*CP*GP*TP*TP*AP*TP*GP*CP*G)-3')
MEAN STRUCTURE. THE STRUCTURE WAS DETERMINED USING SA METHOD WITH DISTANCE RESTRAINTS AND FULL RELAXATION MATRIX REFINEMENT WITH NOE INTENSITY RESTRAINTS OF 50, 80, 160 MS MIXING TIMES
MISMATCHED BASE PAIRING OF 3'-T OF CIS-SYN DIMER WITH A RESIDUE. REFINEMENT DETAILS CAN BE FOUND IN THE JRNL CITATION ABOVE.
SIMULATED ANNEALING AND FULL RELAXATION MATRIX REFINEMENT
DNA, DEOXYRIBONUCLEIC ACID, DNA PHOTOPRODUCT, (6-4) ADDUCT, MUTAGENESIS