Crystal structure of the Escherichia coli YcdX protein reveals a trinuclear zinc active site.

MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDMEDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVD
GEIDCSGKMFDSLDLIIAGFHEPVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKHQVALEINNS
SFLHSRKGSEDNCREVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPERILNVSPRRLLNFLESRGMAPIA
EFADL

0.1 M Tris, 60% AS, 3% MPD, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K

YcdX protein, one zinc ion per subunit, trigonal crystal form

YcdX protein, three zinc ions per subunit, trigonal crystal form

The asymmetric unit contains the entire trimer that corresponds to the oligomeric state of the protein in solution

structural genomics, beta-alpha-barrel, trinuclear zinc, autoinhibition, UNKNOWN FUNCTION