Strand polarity of trinucleotide repeat sequences: NMR studies of parallel/anti-pararell duplex,{d(GAC)3}2
This sequence is found in triplet repeat expansion involving neurogenetic diseases.
This structure was determined using standard 2D homonuclear techniques
structures with the least restraint violations
distance geometry, restraint molecular dynamics
2 mM 5'-d(GACGACGAC), 0.1 M NaCl, 10 mM Sodium Phosphate, 0.1 mM EDTA
DNA trinucleotide repeat, parallel duplex, homo-basepair mismatch, NMR solution structure, DNA