Protein Geranylgeranyltransferase type-I Complexed with GGPP and a Geranylgeranylated KKKSKTKCVIL Peptide Product

Structure of mammalian protein geranylgeranyltransferase type-I

Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

Geranylgeranyl transferase type-1 subunit beta

Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b

CAAX farnesyltransferase subunit alpha,FTase-alpha,Ras proteins prenyltransferase subunit alpha,Type I protein geranyl-geranyltransferase subunit alpha,GGTase-I-alpha

Geranylgeranyl transferase type I subunit beta,GGTase-I-beta,Type I protein geranyl-geranyltransferase subunit beta

MAATEGVGESAPGGEPGQPEQPPPPPPPPPAQQPQEEEMAAEAGEAAASPMDDGFLSLDSPTYVLYRDRAEWADIDPVPQ
NDGPSPVVQIIYSEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNYIIAIIE
EQPKNYQVWHHRRVLVEWLKDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQR
HFVISNTTGYSDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSRYPNLLNQLLDLQPSHSSPYLIAFLVDIYE
DMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHSRESDIPASV

MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQ
VLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGS
FCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVF
SEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDAL
HAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS

ammonium sulfate, sodium citrate, dithiothreitol , pH 6.3, VAPOR DIFFUSION, HANGING DROP, temperature 290K

Co-Crystal Structure Of Rat Protein Farnesyltransferase Complexed With A K-Ras4B Peptide Substrate and Fpp Analog At 2.0A Resolution

Protein Farnesyltransferase Complex With Farnesyl Diphosphate

Structure Of Rat Farnesyl Protein Transferase Complexed With A Cvim Peptide and -Hydroxyfarnesylphosphonic Acid.

Crystal Structure Of Protein Farnesyltransferase At 2.25 Angstroms Resolution

Protein Farnesyltransferase Complexed With Farnesylated K-Ras4B Peptide Product and Farnesyl Diphosphate Substrate Bound Simultaneously

Protein Farnesyltransferase Complexed With A Farnesylated K-Ras4B Peptide Product

Crystal Structure Of Rab Geranylgeranyltransferase From Rat Brain

Geranylgeranyltransferase type-I Complexed with Geranylgeranyl Diphosphate

Geranylgeranyltransferase type-I Complexed with a GGPP Analog and a KKKSKTKCVIL Peptide

Geranylgeranyltransferase type-I Complexed with a Geranylgeranylated KKKSKTKCVIL Peptide Product

THE PEPTIDE WAS CHEMICALLY SYNTHESIZED. THE GERANYLGERANYL LIPID WAS ADDED BY THE ENZYME.

ncs restraints employed during refinement
protein farnesyltransferase alpha subunit (E.C.2.5.1-)/ geranyltransferase type-I beta subunit (E.C.2.5.1-)/transforming protein p21b/ras-related protein RAP-2b
protein geranylgeranyltransferase type-I, GGTase, geranylgeranyl, protein prenylation, CaaX, lipid modification, rap2b, TRANSFERASE