Disulfide Folding Pathways of Cystine Knot Proteins. TYING THE KNOT WITHIN THE CIRCULAR BACKBONE OF THE CYCLOTIDES
This sequence has Cys1 and Cys15, of the naturally occurring kalata B1 peptide, replaced with Ala residues.
The structures are based on a total of 321 NOE derived distance restraints, 19 angle restraints and 20 distance restraints from hydrogen bonds.
cystine knot, triple stranded beta sheet, cyclic peptide, ANTIBIOTIC