Solution Structure of a CCHC Zinc Finger from MOZ
1FY7 contains Esa1 (yeast homologue of MOZ) Histone Acetyltransferase Domain Complexed With Coenzyme A
This structure was determined using standard 2D NMR homonuclear techniques
Structure calculations were performed using the package ARIA 1.1 (Ambiguous Restraints in Iterative Assignment). Final structures are based on 832 unambiguous NOE-derived distance constraints, 1 set of ambiguous NOE-derived distance constraints and 19 additional dihedral angle restraints.
simulated annealing molecular dynamics torsion angle dynamics
0.5mM MOZ protein (533-563), 1mM TCEP, 0.7mM ZnSO4, 95% H2O, 5% D2O
zinc finger, acetyl transferase, DNA BINDING PROTEIN