Crystal Structure of Recombinant Human Fibrinogen Fragment D with the Peptide Ligands Gly-Pro-Arg-Pro-Amide and Gly-His-Arg-Pro-Amide

2.8 A Crystal Structures of Recombinant Fibrinogen Fragment D with and without Two Peptide Ligands: GHRP Binding to the "b" Site Disrupts Its Nearby Calcium-binding Site.

HQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQ
PDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPT
ELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTS
DPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFPQQ

YEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKAN
QQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNG
RTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWW
MNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTIGEGQQHHLGGAK

7% PEG 3350, 12.5mM Calcium Chloride, 2mM Sodium Azide, 50mM Tris pH 8.5, 2mM GHRP-amide, 2mM GPRP-amide, VAPOR DIFFUSION, SITTING DROP, temperature 277K

Crystal Structure Of Fibrinogen Fragment D

Crystal Structure Of Crosslinked Fragment D

Crystal Structure Of Fragment Double-D From Human Fibrin With Two Different Bound Ligands

Crystal Structure Of Fragment Double-D
From Human Fibrin

Crystal Structure Of Fragment Double-D From Human Fibrin With The Peptide Ligand Gly-His-Arg-Pro-Amide

Crystal Structure Of Fragment D From Human Fibrinogen With The Peptide Ligand Gly-His-Arg-Pro-Amide

Crystal Structure of Recombinant Human Fibrinogen Fragment D

Fibrinogen alpha/alpha-E chain,Fibrinogen beta chain, Fibrinogen gamma chain

blood coagulation, fibrinogen, fibrinogen fragment D, recombinant fibrinogen fragment D, recombinant fibrinogen, recombinant fibrinogen fragment D with two peptide ligands, BLOOD CLOTTING