INTERFACIAL ACTIVATION OF THE LIPASE-PROCOLIPASE COMPLEX BY MIXED MICELLES REVEALED BY X-RAY CRYSTALLOGRAPHY

TRP B 30 - SER B 30A OMEGA = 141.29 PEPTIDE BOND DEVIATES SIGNIFICANTLY FROM TRANS CONFORMATION

SER B 30A - PRO B 31 OMEGA = 285.07 PEPTIDE BOND DEVIATES SIGNIFICANTLY FROM TRANS CONFORMATION

The 2.46 Angstroms Resolution Structure of the Pancreatic Lipase Colipase Complex Inhibited by a C11 Alkyl Phosphonate

Structure of the Pancreatic Lipase-Procolipase Complex

VPDPRGIIINLDEGELCLNSAQCKSNCCQHDTILSLLRCALKARENSECSAFTLYGVYYKCPCERGLTCEGDKSLVGSIT
NTNFGICHNVGRSDS

KEVCYERLGCFSDDSPWSGITERPLHILPWSPKDVNTRFLLYTNENPNNFQEVAADSSSISGSNFKTNRKTRFIIHGFID
KGEENWLANVCKNLFKVESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAHAAG
EAGRRTNGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVVGHLDFFPNGGVEMPGCKK
NILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPDGFAGFPCASYNVFTANKCFPCPSGGCPQMGHYADRYPGKTN
DVGQKFYLDTGDASNFARWRYKVSVTLSGKKVTGHILVSLFGNKGNSKQYEIFKGTLKPDSTHSNEFDSDVDVGDLQMVK
FIWYNNVINPTLPRVGASKIIVETNVGKQFNFCSPETVREEVLLTLTPC

LIPASE (E.C.3.1.1.3) COMPLEXED WITH COLIPASE AND PHOSPHOLIPID

MLPLWTLSLLLGAVAGKEVCYERLGCFSDDSPWSGITERPLHILPWSPKDVNTRFLLYTNENPNNFQEVAADSSSISGSN
FKTNRKTRFIIHGFIDKGEENWLANVCKNLFKVESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSP
SNVHVIGHSLGAHAAGEAGRRTNGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVVGH
LDFFPNGGVEMPGCKKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPDGFAGFPCASYNVFTANKCFPCPSGG
CPQMGHYADRYPGKTNDVGQKFYLDTGDASNFARWRYKVSVTLSGKKVTGHILVSLFGNKGNSKQYEIFKGTLKPDSTHS
NEFDSDVDVGDLQMVKFIWYNNVINPTLPRVGASKIIVETNVGKQFNFCSPETVREEVLLTLTPC