STRUCTURAL BASIS FOR HIF-1ALPHA/CBP RECOGNITION IN THE CELLULAR HYPOXIC RESPONSE
Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response.
TAZ1 (Transcription activation zinc finger) domain, Residues 345-439
CTAD (C-Terminal activation) domain, Residues 776-826
HIF-1 ALPHA, ARNT interacting protein, Member of PAS protein 1, MOP1
ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRH DCPVCLPLKNASDKR
SEQEUNCE AUTHOR STATES RESIDUE GLY56 IS A SEQUENCE VARIANT
structures with the least restraint violations, structures with the lowest energy
PEARLMAN, D.A. ET AL. (1995) COMP. PHYS.COMMU.
10MM D-TRIS, 10MM D-DTT, 0.02% NAN3, 0.5MM ZnSO4
ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQIISHWKNCTRH DCPVCLPLKNASDKR