Crystal Structure of CobT complexed with N7-(5'-phosphoribosyl)-2-aminopurine and nicotinate

Structural studies of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica: the apo, substrate, and product-aldimine complexes.

Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

CobT; NN:DBI PRT; N1-alpha-phosphoribosyltransferase; Nicotinate Mononucleotide:5,6-Dimethylbenzimidazole Phosphoribosyltransferase

MQTLHALLRDIPAPDAEAMARTQQHIDGLLKPPGSLGRLETLAVQLAGMPGLNGTPQVGEKAVLVMCADHGVWDEGVAVS
PKIVTAIQAANMTRGTTGVCVLAAQAGAKVHVIDVGIDAEPIPGVVNMRVARGCGNIAVGPAMSRLQAEALLLEVSRYTC
DLAQRGVTLFGVGELGMANTTPAAAMVSVFTGSDAKEVVGIGANLPPSRIDNKVDVVRRAIAINQPNPRDGIDVLSKVGG
FDLVGMTGVMLGAARCGLPVLLDGFLSYSAALAACQIAPAVRPYLIPSHFSAEKGARIALAHLSMEPYLHMAMRLGEGSG
AALAMPIVEAACAMFHNMGELAASNIVLPEGNANAT

ammonium phosphate, pH 6.0, VAPOR DIFFUSION, HANGING DROP at 298K

CobT complexed with 5,6-dimethylbenzimidazole

The biological assembly is a dimer generated from one monomer in asymmetric unit by crystallographic two-fold axis

CobT, cobalamin synthetic enzyme, phosphoribosyltransferase, 5, 6-dimethylbenzimidazole, nicotinate mononucleotide, TRANSFERASE

MQTLHALLRDIPAPDAEAMARTQQHIDGLLKPPGSLGRLETLAVQLAGMPGLNGTPQVGEKAVLVMCADHGVWDEGVAVS
PKIVTAIQAANMTRGTTGVCVLAAQAGAKVHVIDVGIDAEPIPGVVNMRVARGCGNIAVGPAMSRLQAEALLLEVSRYAC
DLAQRGVTLFGVGELGMANTTPAAAMVSVFTGSDAKEVVGIGANLPPSRIDNKVDVVRRAIAINQPNPRDGIDVLSKVGG
FDLVGMTGVMLGAARCGLPVLLDGFLSYSAALAACQIAPAVRPYLIPSHFSAEKGARIALAHLSMEPYLHMAMRLGEGSG
AALAMPIVEAACAMFHNMGELAASNIVLPEGNANAT