HUMAN RENAL DIPEPTIDASE COMPLEXED WITH CILASTATIN

N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE

Crystal Structure of Human Renal Dipeptidase Involved in beta-Lactam Hydrolysis

Crystallization and preliminary X-ray investigation of a glycoprotein, human renal dipeptidase

DFFRDEAERIMRDSPVIDGHNDLPWQLLDMFNNRLQDERANLTTLAGTHTNIPKLRAGFVGGQFWSVYTPCDTQNKDAVR
RTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLIGVEGGHSIDSSLGVLRALYQLGMRYLTLTHSCNTPWAD
NWLVDTGDSEPQSQGLSPFGQRVVKELNRLGVLIDLAHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNVPDDVLRLV
KQTDSLVMVNFYNNYISCTNKANLSQVADHLDHIKEVAGARAVGFGGDFDGVPRVPEGLEDVSKYPDLIAELLRRNWTEA
EVKGALADNLLRVFEAVEQASNLTQAPEEEPIPLDQLGGSCRTHYGYSS

PEG 8000, HEPES, pH 7.6, VAPOR DIFFUSION, HANGING DROP, temperature 283.0K

1ITQ contains the same protein without a ligand.

The biological assembly is a dimer generated from the dimer in the asymmetric unit.

DIPEPTIDASE, GLYCOPROTEIN, MEMBRANE-BOUND, ZINC PROTEASE BETA-LACTAMASE, CILASTATIN, COMPLEX (HYDROLASE-INHIBITOR), HYDROLASE