SOLUTION STRUCTURE OF DESIGNED BETA-SHEET MINI-PROTEIN TH10BOX
Design of a discretely folded mini-protein motif with predominantly beta-structure.
This protein was chemically synthesized.
This structure was determined using standard 2D homonuclear techniques.
structures with the least restraint violations, structures with the lowest energy
The structures are based on 500 distance restraints generated from 667 experimental NOE crosspeaks. Angular restraints enforced amide bond planarity.
de novo protein design three-stranded beta-sheet mini-protein motif TH motif, DE NOVO PROTEIN