STRUCTURE OF THE RGS-LIKE DOMAIN FROM PDZ-RHOGEF
Structure of the RGS-like domain from PDZ-RhoGEF: linking heterotrimeric g protein-coupled signaling to Rho GTPases.
QGVDQSPKPLIIGPEEDYDPGYFNNESDIIFQDLEKLKSRPAHLGVFLRYIFSQADPSPLLFYLCAEVYQQASPKDSRSL GKDIWNIFLEKNAPLRVKIPE(MSE)LQAEIDSRLRNSEDARGVLCEAQEAA(MSE)PEIQEQIHDYRTKRTLGLGSLYG ENDLLDLDGDPLRERQVAEKQLAALGDILSAYAADRSAP(MSE)DFALNTY(MSE)SHAGIRLREA
QGVDQSPKPLIIGPEEDYDPGYFNNESDIIFQDLEKLKSRPAHLGVFLRYIFSQADPSPLLFYLCAEVYQQASPKDSRSL GKDIWNIFLEKNAPLRVKIPEMLQAEIDSRLRNSEDARGVLCEAQEAAMPEIQEQIHDYRTKRTLGLGSLYGENDLLDLD GDPLRERQVAEKQLAALGDILSAYAADRSAPMDFALNTYMSHAGIRLREA
Ammonium Sulfate, PEG 400, Tris-HCl, pH 7.8, VAPOR DIFFUSION, HANGING DROP, temperature 293K
The assymetric unit contains a protein fragment that is a single domain isolated from a multi-domain protein, and is not known to organize into multimers.
RGS-like, Regulator of G protein signaling, GEF, Guanine nucleotide exchange factor, SIGNALING PROTEIN
QGVDQSPKPLIIGPEEDYDPGYFNNESDIIFQDLEKLKSRPAHLGVFLRYIFSQADPSPLLFYLCAEVYQQASPKDSRSL GKDIWNIFLEKNAPLRVKIPEMLQAEIDSRLRNSEDARGVLCEAQEAAMPEIQEQIHDYRTKRTLGLGSLYGENDLLDLD GDPLRERQVAEKQLAALGDILSKYEEDRSAPMDFALNTYMSHAGIRLREA