COVALENT ADDUCT BETWEEN POLYAMINE OXIDASE AND N1ethylN11((cycloheptyl)methyl)4,8diazaundecane at pH 7.0

alpha-D-fucose; 6-deoxy-alpha-D-galactopyranose; D-fucose; fucose

N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE

Structural Bases for Inhibitor Binding and Catalysis in Polyamine Oxidase

ALA B 342 HAS WRONG CHIRALITY AT ATOM CA

ATVGPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNGGKMNPIWPIVNSTL
KLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPNGPATPVDM
VVDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREI
KYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFL
YASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYK
GTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKKMCKYHVQGKYD

A 30 ANGSTROM U-SHAPED CATALYTIC TUNNEL IN THE CRYSTAL STRUCTURE OF POLYAMINE OXIDASE

STRUCTURE OF POLYAMINE OXIDASE IN THE REDUCED STATE

STRUCTURE OF POLYAMINE OXIDASE IN COMPLEX WITH GUAZATINE

STRUCTURE OF POLYAMINE OXIDASE IN COMPLEX WITH 1,8-DIAMINOOCTANE 8DIAZAUNDECANE AT PH 4.6

COVALENT ADDUCT BETWEEN POLYAMINE OXIDASE AND N1ETHYLN11((CYCLOHEPTYL)METHYL)4, 8DIAZAUNDECANE AT PH 4.6

CATALYSES THE OXIDATION OF THE SECONDARY AMINO GROUP OF POLYAMINES (SPERMINE, SPERMIDINE AND THEIR ACETYL DERIVATIVES) THIS IS IMPORTANT FOR REGULATION OF POLYAMINE INTRACELLULAR CONCENTRATION.

FLAVIN-DEPENDENT AMINE OXIDASE, OXIDOREDUCTASE