An affibody in complex with a target protein: structure and coupled folding
CRYSTAL STRUCTURE AT 2.7A RESOLUTION OF A COMPLEX BETWEEN A STAPHYLOCOCCUS AUREUS DOMAIN AND A FAB FRAGMENT OF A HUMAN IGM ANTIBODY
HELIX DETERMINATION METHOD: AUTHOR PROVIDED.
THE STRUCTURE WAS DETERMINED USING TRIPLE-RESONANCE NMR SPECTROSCOPY ON 13C, 15N-LABELED PROTEINS. ONE OF THE SUBUNITS WAS LABELED THE OTHER SUBUNIT WAS KEPT UNLABELED.
LEAST RESTRAINT VIOLATION AND GOOD RAMACHANDRAN PLOTS
REFINEMENT DETAILS CAN BE FOUND IN THE JRNL CITATION ABOVE.
IMMUNOGLOBULIN G BINDING PROTEIN A, ZSPA-1 AFFIBODY
IMMUNE SYSTEM, PROTEIN-PROTEIN INTERACTIONS, PROTEIN ENGINEERING, MOLECULAR RECOGNITION, NMR SPECTROSCOPY, MOLTEN GLOBULE, INDUCED FIT, COUPLED PROTEIN FOLDING, AFFIBODY, IGG BINDING PROTEIN A