CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF THE ULTRASPIRACLE PROTEIN USP, THE ORTHOLOG OF RXRS IN INSECTS

Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects.

AAVQELSIERLLEMESLVADPSEEFQFLRVGPDSNVPPKFRAPVSSLCQIGNKQIAALVVWARDIPHFSQLEMEDQILLI
KGSWNELLLFAIAWRSMEFLTEERDGVDGTGNRTTSPPQLMCLMPGMTLHRNSALQAGVGQIFDRVLSELSLKMRTLRVD
QAEYVALKAIILLNPDVKGLKNRQEVEVLREKMFLCLDEYCRRSRSSEEGRFAALLLRLPALRSISLKSFEHLFFFHLVA
DTSIAGYIRDALRNHAPPIDTNMM

PEG 4000, Tris, NaCl, dithiothreitol, pH 7.5, VAPOR DIFFUSION, HANGING DROP at 277K

ANTIPARALLEL ALPHA-HELICAL SANDWICH, Structural Proteomics in Europe, SPINE, Structural Genomics, gene regulation