CRYSTAL STRUCTURE ANALYSIS OF CHALCONE O-METHYLTRANSFERASE

Structures of two natural product methyltransferases reveal the basis for substrate specificity in plant O-methyltransferases.

ISOLIQUIRITIGENIN 2'-O-METHYLTRANSFERASE

MGNSYITKEDNQISATSEQTEDSACLSAMVLTTNLVYPAVLNAAIDLNLFEIIAKATPPGAFMSPSEIASKLPASTQHSD
LPNRLDRMLRLLASYSVLTSTTRTIEDGGAERVYGLSMVGKYLVPDESRGYLASFTTFLCYPALLQVWMNFKEAVVDEDI
DLFKNVHGVTKYEFMGKDKKMNQIFNKSMVDVCATEMKRMLEIYTGFEGISTLVDVGGGSGRNLELIISKYPLIKGINFD
LPQVIENAPPLSGIEHVGGDMFASVPQGDAMILKAVCHNWSDEKCIEFLSNCHKALSPNGKVIIVEFILPEEPNTSEESK
LVSTLDNLMFITVGGRERTEKQYEKLSKLSGFSKFQVACRAFNSLGVMEFYK

PEG 8000, ammonium acetate, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 4K

Crystal Structure Analysis of Isoflavone O-methyltransferase

Crystal Structure Analysis of Selenomethionine substituted IOMT

Crystal Structure Analysis of Selenomethionine Substituted Chalcone O-methyltransferase

The biological assembly is a dimer constructed from the monomer by a two-fold rotation.

protein-substrate, protein-product complex, TRANSFERASE