CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTION PRIMER TRNA(LYS3)
The crystal structure of HIV reverse-transcription primer tRNA(Lys,3) shows a canonical anticodon loop.
Molecular blocs in tRNAs that could prevent +1 frameshifting
Studies on the ternary initiation complex of HIV-1 reverse transcription and crystallographic structures of two partners
HIV-1 REVERSE TRANSCRIPTION PRIMER TRNA(LYS3)
GCCCG(2MG)AUA(2MG)CUCAG(H2U)CGG(H2U)AGAGCA(PSU)CAGACU(70U)UU(12A)A(PSU)CUGAGG (7MG)(H2U)(5MC)(5MC)AGGG(2MU)(PSU)CA(1MA)GUCCCUGUUCGGGCGCCA
THIS SEQUENCE OCCURS NATURALLY IN HUMANS, BOVINES AND CHICKENS
50 mM MES-KOH pH 5.6, 1.6 to 1.8 M Li2SO4, 10 mM MgCl2, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 293K
R and free R improved by 12% and 11% respectively by a proper mask definition (see primary ref.)
modified CNS libraries (Parkinson et al.)
mammalian transfert ribonucleic acid, HIV-1 primer tRNA, amino acid transport, canonical tRNA structure, canonical anticodon, frameshifting, codon/anticodon mimicry, modified bases, RNA