AVERAGE NMR SOLUTION STRUCTURE OF THE BIR-3 DOMAIN OF XIAP
NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP.
GSHMSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDP WEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT
50 mM bis-Tris-d12 (pH=7.2), 300 mM KCl, 50 uM Zinc Acetate, 1 mM DTT; 95% H2O, 5% D2O
Bir3 domain, inhibitor of apoptosis protein XIAP, Zinc finger, caspase-9 inhibition, apoptosis inhibitor
SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQH AKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT