Crystal structure of the TPR2A domain of HOP in complex with the HSP90 peptide MEEVD
Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine.
GKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAK AYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERL
PEG MME 2000, TRIS, Nickel chloride, Xylitol, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
This sequence occurs naturally in humans
CRYSTAL STRUCTURE OF THE TPR2A-DOMAIN OF HOP IN COMPLEX WITH THE HSP90-PEPTIDE MEEVD
Hop, Tpr-Domain, Peptide-Complex, Helical Repeat, Hsp90, Protein Binding, CHAPERONE