Crystal structure of methanobacterium thermoautotrophicum nicotinamide mononucleotide adenylyltransferase with bound NAD+

Midwest Center for Structural Genomics (MCSG)

Northeast Structural Genomics Consortium (NESG)

Insights into ligand binding and catalysis of a central step in NAD+ synthesis: structures of Methanobacterium thermoautotrophicum NMN adenylyltransferase complexes.

NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE

MMTMRGLLVGRMQPFHRGHLQVIKSILEEVDELIICIGSAQLSHSIRDPFTAGERVMMLTKALSENGIPASRYYIIPVQD
IECNALWVGHIKMLTPPFDRVYSGNPLVQRLFSEDGYEVTAPPLFYRDRYSGTEVRRRMLDDGDWRSLLPESVVEVIDEI
NGVERIKHLAKKEVSELGGIS

1.5 M LiSO4, 0.1 M HEPES, pH 7.5, VAPOR DIFFUSION, HANGING DROP

Northeast Structural Genomics Consortium

DINUCLEOTIDE BINDING FOLD, Structural Genomics, PSI, Protein Structure Initiative, Midwest Center for Structural Genomics, MCSG, Northeast Structural Genomics Consortium, NESG, TRANSFERASE