CRYSTAL STRUCTURE OF MUTUALLY GENERATED MONOMERS OF DIMERIC PHOSPHORIBOSYLANTRANILATE ISOMERASE FROM THERMOTOGA MARITIMA

Structure and function of mutationally generated monomers of dimeric phosphoribosylanthranilate isomerase from Thermotoga maritima.

PROTEIN (PHOSPHORIBOSYLANTRANILATE ISOMERASE)

MVRVKICGITNLEDALFSVESGADYVGFVFYPKSKRYISPEDARRISVELPVERVGVFVNEEPEKILDVASYVQLNAVQL
HGEEPIELCRKIAERILVWKAVGVSNERDMERALNYREFPILLDTKTPEYGGSGKTFDWSLILPYRDRFRYLVLSGGLNP
ENVRSAIDVVRPFAVDVSSGVEAFPGKKDHDSIKMFIKNAKGL

1 MM EDTA 0.5 MM DTT 0.1 M HEPES/NAOH 16.7 MG/ML PROTEIN 0.75 M POTASSIUM DIHYDROGEN PHOSPHATE 0.75 M SODIUM DIHYDROGEN PHOSPHATE, pH 7.5, VAPOR DIFFUSION, HANGING DROP

ISOMERASE, OLIGOMERISATION, THERMOSTABILITY, THERMOTOGA MARITIMA, PROTEIN ENGINEERING, DIMER EVOLUTION