THE CRYSTAL STRUCTURE OF E. COLI PSEUDOURIDINE SYNTHASE I AT 1.5 ANGSTROM RESOLUTION

The structural basis for tRNA recognition and pseudouridine formation by pseudouridine synthase I.

PPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTALRKDAAWTLG
VNANLPGDIAVRWVKTVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGENDFTSFRA
VQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRTLAAATAKAEGLY
LVAVDYPDRYDLPKPPMGPLFLAD

MES BUFFER, pH 6.5, MICRODIALYSIS, temperature 298K

USED WEIGHTED FULL MATRIX LEAST SQUARES PROCEDURE

ALPHA/BETA FOLD, RNA-BINDING MOTIF, RNA-MODIFYING ENZYME, LYASE