CRYSTAL STRUCTURE OF A MAT-ALPHA2 HOMEODOMAIN-OPERATOR COMPLEX SUGGESTS A GENERAL MODEL FOR HOMEODOMAIN-DNA INTERACTIONS

Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions.

Crystallization and Preliminary X-Ray Diffraction Studies of a MAT-Alpha2-DNA Complex

DNA (5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*CP*AP*TP*TP*TP*AP*C P*AP*CP*GP*C)-3')

DNA (5'-D(*TP*GP*CP*GP*TP*GP*TP*AP*AP*AP*TP*GP*AP*AP*TP*TP*A P*CP*AP*TP*G)-3')

(DA)(DC)(DA)(DT)(DG)(DT)(DA)(DA)(DT)(DT)(DC)(DA)(DT)(DT)(DT)(DA)(DC)(DA)(DC)(DG)
(DC)

(DT)(DG)(DC)(DG)(DT)(DG)(DT)(DA)(DA)(DA)(DT)(DG)(DA)(DA)(DT)(DT)(DA)(DC)(DA)(DT)
(DG)

TKPYRGHRFTKENVRILESWFAKNIENPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEKTITIAPELADLLSGEPLAK
KKE

PROTEIN-DNA COMPLEX, DOUBLE HELIX, DNA BINDING PROTEIN-DNA COMPLEX