STRUCTURAL EFFECTS INDUCED BY MUTAGENESIS AFFECTED BY CRYSTAL PACKING FACTORS: THE STRUCTURE OF A 30-51 DISULFIDE MUTANT OF BASIC PANCREATIC TRYPSIN INHIBITOR
THE FOLLOWING RESIDUES MODELLED WITH 2 SIDE CHAIN CONFORMATIONS: GLU A 7, ARG A 17, ARG A 39, GLU A 49, ASP B 3, ARG B 17, ARG B 39, ARG B 42, GLU B 49.
Structural Effects Induced by Removal of a Disulfide Bridge: The X-Ray Structure of the C30A(Slash)C51A Mutant of Basic Pancreatic Trypsin Inhibitor at 1.6 Angstroms
THERE IS A UNIQUE SALT-BRIDGE BETWEEN THE N AND C TERMINALS OF MOLECULES WITH RESIDUE NUMBERS 1 - 58, WHICH HAS BEEN SEEN IN SOLUTION (NMR) BUT NEVER CRYSTALLOGRAPHICALLY.
BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI, BASIC) MUTANT WITH CYS 30 REPLACED BY VAL AND CYS 51 REPLACED BY ALA (C30V,C51A)
THE TRANSFORMATION PRESENTED ON *MTRIX* RECORDS BELOW WILL GENERATE APPROXIMATE COORDINATES FOR CHAIN B WHEN APPLIED TO CHAIN A.
MKMSRLCLSVALLVLLGTLAASTPGCDTSNQAKAQRPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNF KSAEDCMRTCGGAIGPWENL